mdma
Efforts to make MDMA legally available as a psychotherapeutic catalyst hit a daunting roadblock on Tuesday when an expert panel overwhelmingly voted to recommend that the Food and Drug Administration (FDA) reject a new drug application that Lykos Therapeutics submitted in February. Members of the panel expressed several concerns about two Phase 3 studies of MDMA's safety and effectiveness in treating post-traumatic stress disorder (PTSD), including unblinding of subjects, potential underreporting of adverse events, and allegedly inadequate assessment of MDMA's abuse potential. "We are disappoi...
Reason
Washington (AFP) - A panel of US health experts convened by the Food and Drug Administration on Tuesday overwhelmingly voted against the use of MDMA, commonly known as ecstasy, to treat post-traumatic stress disorder. PTSD, a debilitating mental health condition that develops after a person experiences or is threatened by traumatic events such as death, combat or sexual assault, affects an estimated five percent of Americans in any given year. But pharmaceutical treatment options are so far limited to two antidepressants that require three months of dosing to take effect, and response rates t...
AFP
Washington (AFP) - A panel of US health experts convened by the Food and Drug Administration (FDA) are meeting Tuesday to weigh the benefits and risks of using MDMA, commonly known as ecstasy, to treat post-traumatic stress disorder. PTSD, a debilitating mental health condition that develops after a person experiences or is threatened by traumatic events such as death, combat, or sexual assault, affects an estimated five percent of Americans in any given year. But treatment options are so far limited to two antidepressants that require three months of dosing to take effect, and response rates...
AFP
A recent case study published in Clinical Case Reports describes the journey of a 41-year-old woman who turned to psilocybin and MDMA to manage her debilitating post-COVID symptoms. The paper raises the intriguing possibility, which is far from certain, that psychedelic substances might help alleviate the psychological and cognitive symptoms associated with Long-COVID. Long-COVID, also known as post-acute sequelae of SARS-CoV-2 infection, encompasses a range of symptoms that persist well beyond the initial recovery from COVID-19. These symptoms can include fatigue, cognitive impairment, anxiet...
PsyPost
A recent case study published in Clinical Case Reports describes the journey of a 41-year-old woman who turned to psilocybin and MDMA to manage her debilitating post-COVID symptoms. The paper raises the intriguing possibility, which is far from certain, that psychedelic substances might help alleviate the psychological and cognitive symptoms associated with Long-COVID. Long-COVID, also known as post-acute sequelae of SARS-CoV-2 infection, encompasses a range of symptoms that persist well beyond the initial recovery from COVID-19. These symptoms can include fatigue, cognitive impairment, anxiet...
PsyPost (UK)
A recent case study published in Clinical Case Reports describes the journey of a 41-year-old woman who turned to psilocybin and MDMA to manage her debilitating post-COVID symptoms. The paper raises the intriguing possibility, which is far from certain, that psychedelic substances might help alleviate the psychological and cognitive symptoms associated with Long-COVID. Long-COVID, also known as post-acute sequelae of SARS-CoV-2 infection, encompasses a range of symptoms that persist well beyond the initial recovery from COVID-19. These symptoms can include fatigue, cognitive impairment, anxiet...
PsyPost (CA)
Interviews conducted with two clinicians specializing in treating patients with borderline personality disorder and two providing MDMA-assisted therapy primarily for individuals with Post-Traumatic Stress Disorder (PTSD) have yielded insights into the similarities between these disorders. Based on this, the authors of the research suggest that the potential benefits of MDMA in treating borderline personality disorder warrant further detailed exploration. The paper was published in Journal of Psychedelic Studies. Borderline personality disorder is a complex and often debilitating mental health ...
PsyPost
New research suggests that low doses of MDMA, commonly known as ecstasy, can help to reduce the challenging effects associated with psychedelic drugs like LSD (lysergic acid diethylamide) and psilocybin, the active component in magic mushrooms. The findings, published in Scientific Reports, shed new light on the effects of “candy flipping” and “hippy flipping”‘ – terms used for the co-administration of LSD or psilocybin with MDMA. MDMA, psilocybin, and LSD are psychoactive substances known for their potent effects on human perception, mood, and consciousness. The motivation for this study was ...
PsyPost
MDMA-assisted therapy for post-traumatic stress disorder (PTSD) appears to have positive effects on mental processes related to self-experience, such as emotional awareness and self-compassion, which are often linked to poor treatment outcomes in traditional therapies, according to new research published in PLOS One. These findings highlight MDMA’s potential in addressing deeper psychological issues that typically hinder successful treatment. MDMA, or 3,4-methylenedioxymethamphetamine, is a synthetic compound commonly known in its recreational form as ecstasy or molly. Initially synthesized in...
PsyPost
The strength of the relationship between therapists and patients appears to play a crucial role in the effectiveness of MDMA-assisted psychotherapy in treating posttraumatic stress disorder (PTSD), according to new research published in the European Journal of Psychotraumatology. The findings provide evidence that a stronger therapeutic alliance correlates with better treatment outcomes for patients. PTSD is a mental health condition that can develop after an individual experiences or witnesses a traumatic event, such as warfare, a natural disaster, a serious accident, or physical or sexual as...
PsyPost
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