psychopharmacology
A recent study conducted in Austria demonstrated that administering drugs that block opioid and dopamine receptors in the brain leads to reduced neural activity in the medial orbitofrontal cortex and several other regions during the receipt of valued rewards. However, these drugs did not show any observable effects on behavior. The paper was published in Human Brain Mapping. Rewards are stimuli perceived by the brain as beneficial or desirable, eliciting positive emotional responses. These responses motivate behaviors aimed at obtaining such rewards. Rewards may be tangible, like food and mone...
PsyPost (CA)
A recent study conducted in Austria demonstrated that administering drugs that block opioid and dopamine receptors in the brain leads to reduced neural activity in the medial orbitofrontal cortex and several other regions during the receipt of valued rewards. However, these drugs did not show any observable effects on behavior. The paper was published in Human Brain Mapping. Rewards are stimuli perceived by the brain as beneficial or desirable, eliciting positive emotional responses. These responses motivate behaviors aimed at obtaining such rewards. Rewards may be tangible, like food and mone...
PsyPost
A recent study conducted in Austria demonstrated that administering drugs that block opioid and dopamine receptors in the brain leads to reduced neural activity in the medial orbitofrontal cortex and several other regions during the receipt of valued rewards. However, these drugs did not show any observable effects on behavior. The paper was published in Human Brain Mapping. Rewards are stimuli perceived by the brain as beneficial or desirable, eliciting positive emotional responses. These responses motivate behaviors aimed at obtaining such rewards. Rewards may be tangible, like food and mone...
PsyPost (UK)
In a new study published in Nature Communications, researchers from the University of Colorado Anschutz Medical Campus have discovered preliminary evidence suggesting that the use of antidepressants during pregnancy can have significant effects on brain development, specifically impacting the development of connections within the brain’s prefrontal cortex. This region of the brain is crucial for complex cognitive functions such as decision-making, personality expression, and social behavior. The study, conducted on rodents, sheds light on the role that serotonin, a key neurotransmitter affecte...
PsyPost (CA)
Doxycycline, a widely used antibiotic, might help reduce the addictive effects of drugs like morphine and cocaine, according to new research published in Progress in Neuro-Psychopharmacology and Biological Psychiatry. This finding opens up new possibilities for treating substance use disorders, offering hope for more effective interventions. Substance use disorders represent a major public health challenge globally. Characterized by the compulsive use of addictive drugs, these disorders lead to severe behavioral and neural changes, posing significant treatment challenges. Existing treatments a...
PsyPost
In a recent study published in Nature Communications, scientists have discovered how different drug administration methods affect brain function and the experience of drug reward. The findings are vital in unraveling the complex mechanisms behind drug addiction and in developing targeted interventions for substance use disorders. Previous research has long established the connection between dopamine, a key neurotransmitter in the brain, and its role in the rewarding effects of drugs. This connection is a crucial factor in the development of addiction. However, there was a gap in understanding ...
PsyPost
Imagine a world where you could control your sense of time. Where trips to the dentist flew by in a second and holidays felt like they lasted forever. Time altering pills may sound like science fiction but the time warping effects of psychoactive drugs suggest that deliberate time manipulation may be possible. Drug induced time-warps are a widely reported phenomenon by recreational drug users. My 2022 study suggested that over 75% of people who had recently used cocaine, MDMA (also known as ecstasy) and cannabis reported distortions to the passage of time during drug use. The participants said...
PsyPost
In a new study published in the Journal of Affective Disorders, researchers discovered that women currently using birth control pills show a lower prevalence of major depression compared to those who have stopped using them. The birth control pill has been a pivotal element in women’s health for decades, used not only for preventing pregnancies but also for managing menstrual symptoms. Despite its widespread use, there has been ongoing debate and concern regarding its potential impact on mental health, particularly depression. Previous studies have shown mixed results – some suggesting a link ...
PsyPost
In a recent study published in the Journal of Neuroscience, researchers found that individuals with Attention-Deficit/Hyperactivity Disorder (ADHD) show reduced motivation to engage in effortful activities, both cognitive and physical, which can be significantly improved with amphetamine-based medications. ADHD, a common behavioral disorder, is often associated with difficulty in maintaining attention, hyperactivity, and impulsiveness. Traditionally, ADHD has been viewed primarily through the lens of these symptoms. However, recent research suggests that motivation, particularly the willingnes...
PsyPost
New research provides evidence that women using birth control pills experience different stress and inflammation responses compared to those not using these contraceptives. The findings, published in Brain, Behavior, and Immunity, shed light on the complex ways in which hormonal contraceptives can influence the body’s psychophysiological reactions. For years, hormonal contraceptives, commonly known as birth control pills, have been an important part of many women’s lives. Over 300 million women worldwide use them. While these pills are well-studied for their safety and effectiveness in prevent...
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