Visiting German Foreign Minister had to seek shelter during her visit to Odessa on Saturday evening when air raid sirens went off.
The alarm was triggered on Saturday evening at 9:48 pm (1948 GMT). Air raid sirens could be heard in the port city. The alarm was lifted at 10:07 pm.
The Green Party politician took refuge in the shelter of her hotel together with members of her delegation and other guests, a dpa reporter learned.
An explosion was then heard in the Odessa region. It remained unclear whether there was a rocket hit or whether the Ukrainian air defences had blocked the projectile.
There was no immediate information on possible damage or victims.
Two Russian drone attacks left a total of four dead and several injured in the city of Odessa shortly before Baerbock's visit.
The top German diplomat was in Ukraine on a trip with Ukraine's Foreign Minister Dmytro Kuleba to mark the second anniversary of the beginning of Russia's full-scale invasion of its neighbour Ukraine.