Tokyo's Nikkei index opened nearly flat Wednesday as an overnight record high on the U.S. Dow Jones index was offset by worries over a resurgence of COVID-19 cases across Japan.
In the first 15 minutes of trading, the 225-issue Nikkei Stock Average fell 8.80 points, or 0.03 percent, from Tuesday to 29,292.99. The broader Topix index of all First Section issues on the Tokyo Stock Exchange was up 7.79 points, or 0.38 percent, at 2,038.01.
Decliners were led by precision instrument and pharmaceutical issues, while transportation equipment and insurance issues led gainers.
At 9 a.m., the dollar fetched 116.16-19 yen compared with 116.07-17 yen in New York and 115.73-75 yen in Tokyo at 5 p.m. Tuesday.
The euro was quoted at $1.1281-1285 and 131.04-131.12 yen against $1.1281-1291 and 130.98-131.08 yen in New York and $1.1290-1292 and 130.66-70 yen in Tokyo late Tuesday afternoon.